Cell Function Reagents and Kits
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Filtered Search Results
Medchemexpress LLC MRS2500 tetraammonium | 630103-23-0 | 99.9% | 629.28 | 1 ML
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MRS2500 tetraammonium is a potent, selective, and stable antagonist of the P2Y1 receptor (Ki=0.78 nM for recombinant human P2Y1 receptor). It inhibits the ADP-induced aggregation of human platelets with an IC50 value of 0.95 nM, demonstrating antithrombotic activity.
- Potent, selective, and stable antagonist of the P2Y1 receptor.
- Inhibits ADP-induced aggregation of human platelets with an IC50 of 0.95 nM.
- Exhibits antithrombotic activity.
- Decreases acute systemic thromboembolism through selective inhibition of the P2Y1 receptor.
- Showed strong antithrombotic efficacy in preventing arterial thrombosis in the monkey ECAT model.
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Apexbio Technology LLC Calcein AM Cell Viability Assay Kit 500T
The Calcein AM Cell Viability Assay Kit employs calcein AM a cell-permeable fluorescent probe for assessing viable cell populations Calcein AM readily crosses membranes due to its hydrophobic acetoxymethyl (AM) modification Within viable cells intracellular esterases cleave calcein AM releasing calcein a fluorescent molecule retained by healthy cells emitting green fluorescence proportional to viable cell numbers Cells lacking this enzymatic activity typically dead or compromised remain unstained This assay is commonly applied in studies evaluating cell proliferation cytotoxicity or cell survival under various experimental conditions Compared to assays such as MTT and CCK-8 the calcein AM method allows detection of smaller cell populations often down to approximately 50 cells and provides results within approximately 30 minutes after treatment
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Miltenyi Biotec, Inc. 7-AAD Solution
Evaluation of cell viability in the analysis of human leukocytes in peripheral blood..
This product is subject to the following: Miltenyi Biotec, Inc. Terms and Conditions of Sale For Products and Services
Aat Bioquest BAPTA tetrapotassium salt CAS 73630-08-7 (100 mg)
BAPTA 12-biso-aminophenoxyethane-NNNN-tetraacetic acid is a water-soluble and cell-impermeable calcium chelator. This catalog is for 100 mg.
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Medchemexpress LLC 2-NBDG 25mg | 186689-07-6 | 342.26 | C12H14N4O8 | 25 MG
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2-NBDG is a fluorescently labeled deoxyglucose analog used to directly monitor glucose uptake in living cells and tissues. It is excitable at 488 nm and produces environment-sensitive fluorescence suitable for real-time confocal, high-resolution, or wide-field fluorescence microscopy and for flow cytometry. Supplied as a 25 mg solid with high reported purity.
- Directly reports cellular glucose uptake in live-cell assays.
- Compatible with flow cytometry and fluorescence microscopy.
- Excitable at 488 nm (argon laser).
- Environment-sensitive fluorescence for intracellular localization studies.
- High reported purity for reliable experimental results.
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MEDCHEMEXPRESS LLC CALCEIN BLUE 25MG
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501871908 CALCEIN BLUE 25MG
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MEDCHEMEXPRESS LLC DABSYL CHLORIDE 50MG
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501871910 DABSYL CHLORIDE 50MG
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MEDCHEMEXPRESS LLC FURA-2 AM 1MG
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501871915 FURA-2 AM 1MG
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TISSUEARRAY COM LLC CERVICAL CANCER TMA
NC2458906 CERVICAL CANCER TMA
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Apexbio Technology LLC Indigo 482-89-3 20mg
Indigo (482-89-3) is a deep-colored indole-based dye that can be isolated from certain plant species and related organisms Explicit information regarding its molecular target mechanism of action activity type experimental models or quantitative activity metrics is not provided Based on available data indigo holds research potential as a colorant and staining agent in histological and biological studies
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![Medchemexpress LLC 5-chloro-N-[2-(4-hydroxysulfamoyl-phenyl)-ethyl]-2-methoxybenzamide | 2112809-98-8 | 98.4% | 384.83 | C16H17ClN2O5S | 10 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000226332.png-250.jpg)
Medchemexpress LLC 5-chloro-N-[2-(4-hydroxysulfamoyl-phenyl)-ethyl]-2-methoxybenzamide | 2112809-98-8 | 98.4% | 384.83 | C16H17ClN2O5S | 10 MG
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JC-171 is a selective NLRP3 inflammasome inhibitor that blocks LPS/ATP-induced interleukin-1β (IL-1β) release from macrophages (IC50 = 8.45 μM). It has demonstrated activity in vitro and in vivo, including reduction of disease severity in mouse EAE models, and is supplied as a high-purity research chemical.
- Selective NLRP3 inflammasome inhibitor; IC50 = 8.45 μM for LPS/ATP-induced IL-1β release in J774A.1 macrophages.
- Shown to reduce disease severity in mouse EAE models and lower Th17 cell frequency.
- High purity (98.4%); molecular weight 384.83 g·mol⁻¹; formula C16H17ClN2O5S.
- Soluble ≥ 2.08 mg/mL in recommended vehicles for in vivo dosing.
- Available in small research pack sizes, including 10 mg.
- Recommended storage: powder at -20°C; prepared solutions at -80°C to limit freeze-thaw.
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Aat Bioquest LysoBrite Red DND-99 (500 Tests)
LysoBrite Red DND-99 is chemically same to the LysoTracker Red DND-99 used for labeling and tracking acidic organelles in live cells LysoTracker is the trademark of ThermoFisher. This catalog is for 500 Tests.
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Biotium Fura-2, AM Ester
Fura-2, AM ester is an intracellular fluorescent calcium indicator, and the preferred dye for ratiometric imaging microscopy. The membrane-permeant AM ester can be loaded into cells via incubation, but due to limited water solubility, a mild detergent Pluronic F-127 is often used to facilitate cell loading. Fura-2, AM ester itself does not bind Ca2, but intracellular esterases readily hydrolyze it to Fura-2. Upon calcium binding, the excitation maximum of Fura-2 undergoes a blue-shift from 363 nm (no Ca2) to 335 nm (high Ca2) while the emission maximum is relatively unchanged. Measure by flow cytometry, fluorescence microscopy, or certain fluoresence microplate readers. Properties: Light yellow solid soluble in DMSO; Store at -20°C, protect from light, especially in solution; Kd: 145 nM (22°C, pH 7.2 buffer); Ex/Em = 363/512 nm, e = 27,000 M-1cm-1 (no Ca2); Ex/Em 335/505 nm, e = 35,000 M-1cm-1 (high Ca2); C44H47N3O24; MW: 1001.9; [108964-32-5].
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Cayman Chemical RedDotM2 VIabIlIty Dye 50uL
A p-phenylenediamine and non-oxidized version of DPPD-Q toxic to the aquatic bacterium V. fischeri (EC50 0.02 mg/L) reduces the viability of HepG2 cancer cells at 10 UG/L decreases urinary protein levels and serum levels of bilirubin in male rats at 100 mg/kg per day increases the time in gestation for female rats when administered to pregnant dams at 50 and 300 mg/kg per day has been found in water treatment plant influent biosolids and landfill leachates indoor dust and in PM2.5 samples collected in cities and by roadsides
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